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DISCLOSURE: Longevity. Technology (a brand of First Longevity Limited) has been contracted by the company featured in this article to support its current funding round. Qualifying investors can find out more via the Longevity. Technology investor portal.

British regenerative medicine company Videregen is on a mission to cure chronic diseases and is targeting the human immune system through its work to regenerate the thymus. Building on groundbreaking work conducted at the Francis Crick Institute, Videregen believes its technology holds the potential to restore the function of the aging immune system. The company is already approved for initial clinical trials of its technology in respiratory disease and is working towards trials of its regenerative thymus technology within three years.

Longevity Technology: The thymus is a small but important organ in the immune system and is responsible for the development and maturation of critical T cells. It plays a key role in our early development, but declines significantly as we age, along with the functionality of our immune system, and its decline is linked to several age-related and chronic diseases. Videregen is betting that its technology can help restore the thymus, potentially rejuvenating our immune system in the process. To learn more, we spoke to the company’s CEO, Dr Steve Bloor.

A stem cell therapy treatment developed by Duke-NUS Medical School researchers for heart failure has shown promising results in preclinical trials. These cells, when transplanted into an injured heart, are able to repair damaged tissue and improve heart function, according to a study published in the journal npj Regenerative Medicine.

Longevity. Technology: The most common cause of death worldwide is ischemic heart disease, which is caused by diminished blood flow to the heart. When blood flow to the heart is blocked, the heart muscle cells die – a condition termed myocardial infarction or heart attack, something that happens to 805,000 people a year in the US [1].

In the Duke-NUS study, a unique new protocol was used where pluripotent stem cells were cultivated in the laboratory in order to grow into heart muscle precursor cells – these cardiomyocyte progenitors can develop into various types of heart cells, through a process called cell differentiation in which dividing cells gain specialised functions. During preclinical trials, the precursor cells were injected into the area of the heart damaged by myocardial infarction, where they were able to grow into new heart muscle cells, restoring damaged tissue and improving heart function.

In an interview with GQ, 54-year-old David Sinclair says his lifestyle changes got him back to his “20-year-old brain.”

New research published in Scientific Reports suggests that microbes in the human gut and mouth can impact how long people live [1].

Bacteria and other microbes are often associated with diseases, but disease-causing microbes are only a minority. The majority of microbes are harmless or beneficial to humans, and we have millions of them living inside and outside us. Researchers refer to this community as the microbiota.

In previous research, scientists had noticed an association between microbiota and longevity [2]. However, the association between two things does not necessarily mean that one is causing the other. Therefore, in this new paper, researchers explored potential causal relationships between gut and mouth microbes’ composition and longevity in order to determine what compositions of microbiota result in increases or decreases in lifespan.

On January 23, 2023, we celebrated the expansion of the SENS Research Foundation’s Research Center, more than doubling its capacity.

California Dignitaries Alison Hicks, Mayor of Mountain View, Peter Katz, President of the Mountain View Chamber of Commerce, Marc Berman, California State Assemblymember, and Saul Miranda, District Representative, were present to officiate the ribbon-cutting ceremony.

SENS Research Foundation was awarded a Certificate of Recognition by Senator Josh Becker, California State Senate.

Video by Vecc Schiafino.

Accelerating Effective Treatments To Prevent And Reverse Human Age-Related Disease — Dr. Aubrey de Grey, Ph.D. — President & Chief Science Officer, Longevity Escape Velocity Foundation (LEVF)


Dr. Aubrey de Grey, Ph.D., is President & Chief Science Officer of the Longevity Escape Velocity (LEV) Foundation (https://www.levf.org/), an organization focused on proactively identifying and addressing the most challenging obstacles on the path to the widespread availability of genuinely effective treatments to prevent and reverse human age-related disease.

Dr. de Grey is internationally recognized as a visionary biomedical gerontologist who devised the Strategies for Engineered Negligible Senescence: a comprehensive set of methods to rejuvenate the human body, thereby preventing age-related ill health and mortality. He has co-founded multiple non-profit organizations – including Methuselah Foundation, SENS Research Foundation, and now LEV Foundation – to specifically enable and accelerate its development and clinical translation.

Dr. de Grey received his BA in Computer Science and Ph.D. in Biology from the University of Cambridge in 1985 and 2000, respectively. He is the author of The Mitochondrial Free Radical Theory of Aging (1999), Ending Aging (2007), and a large number of academic papers.

Dr. de Grey is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the advisory boards of numerous scientific journals and research organizations. He is a prolific speaker who regularly presents at conferences and events world-wide.

https://youtube.com/watch?v=K-70S1oycR4&feature=share

1:33…“10 years”.


Dive into the fascinating world of aging research with this thought-provoking video. Join us as we explore the latest breakthroughs and scientific advancements on the quest to reverse aging. Discover the potential strategies, therapies, and technologies that hold promise for extending healthspan and pushing the boundaries of human longevity. Get ready to embark on an exciting journey towards understanding the future of aging reversal.

Credits/source: https://www.youtube.com/@peterdiamandis.

#Aging #ReverseAging #Longevity #Healthspan #AgingResearch #AntiAging #LongevityTechnologies #AgingReversal #FutureOfAging

At 19:46 Aubrey has a chart for 150 year olds and 1,000 year olds.


6th Edition: AGING & GERONTOLOGY — Sciinov Group.
www.agingcongress.com.

Aubrey De Grey.
President & CSO, LEV Foundation, USA
Title: Taking Rejuvenation to Longevity escape velocity.

Sciinov Group is a specialized international events organizer, and provider of customized data intelligence databases, trends and insights that solve information challenges and caters organizations needs.

Sciinov Conferences mission is to benefit attendees by networking their peers, often potential clients and learn from the high quality of information delivered by the expert speakers.

I believe that homelessness is often seen in America or other parts of the world as bad but with Finland they have found a housing first approach which has stopped nearly all homelessness there. I believe also regenerative medicine and lots of transhumanistic approaches to medicine would help end their aging and even repair their body if needed. Also if we research the brain we can finally discover and repair genes throughout the body essentially bringing them back near perfect and beyond. Along with ethical approaches towards a more cultural relativistic approach to all humans could show everyone how to coexist. It is still a problem of aging though which is still curable and in extreme cases will be eventually solved in the future. I think with a more comprehensive understanding of all transhumansistic medicine it would be possible to save all lives so no one is left behind.


OK, so the Finns are more generous and just shell out a lot more to help the homeless, right? Actually not. The Finns are simply smarter.

Instead of abandoning the homeless, they housed them. And that led to an insight: people tend to function better when they’re not living on the street or under a bridge. Who would have guessed?

It turns out that, given a place to live, Finland’s homeless were better able to deal with addictions and other problems, not to mention handling job applications. So, more than a decade after the launch of the “Housing First” policy, 80 per cent of Finland’s homeless are doing well, still living in the housing they’d been provided with — but now paying the rent on their own.