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Should You Take Experimental Life Extension Drugs?

My output on my personal blog has been low lately. That’s largely because I’m pushing hard to finish a complete draft of my book on biostasis. If I can keep up the pace, I expect to finish a draft around the end of the year or in January 2025. The blog entries I have written have been on our group blog for Biostasis Technologies. Subscribers will probably enjoy my October 29 entry:

I look at the origins of effective accelerationism (e/acc) and its unacknowledged roots in extropian transhumanism as well as in several Singularitarian writers. Noah Smith has noted the “extropian enthusiasm” of e/acc. The original essays by the e/acc founders can be difficult to distill down so I outline the basics of e/acc and then survey the many flavors of accelerationism. I point out errors in e/acc’s contrast with transhumanism. That is followed by a critique of the injunction to “follow the will of the universe.” Despite errors and shortcomings I conclude that e/acc is more right than wrong. From the perspective of the central important of life extension, I outline what might be called long/acc or longevity accelerationism.

Exosomes Break Rat Lifespan Record

This has to do with E5, but last I checked they were only doing skin rejuvenation treatments in people.


In Aging Cell, researchers have published their findings that exosomes, which we have previously reported to extend the lives of mice, also extend the lives of rats.

Known to be effective

Exosomes, a subset of extracellular vesicles (EVs), can be visualized as messages and packages that cells send to one another. Along with lifespan studies, EVs have been investigated for their ability to treat liver fibrosis, and they have been identified as potential biomarkers of disease [1].

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