Lifeboat Foundation

The World Health Organization on Wednesday declared the ongoing mpox outbreak in Africa a global health emergency.

WHO convened its emergency committee amid concerns that a deadlier strain of the virus, clade Ib, had reached four previously unaffected countries in Africa. This strain had previously been contained to the Democratic Republic of Congo.

The independent experts met virtually Wednesday to advise WHO Director-General Tedros Adhanom Ghebreyesus on the severity of the outbreak. After that consultation, he announced that he had declared a public health emergency of international concern — the highest level of alarm under international health law.

Alarmed by the surge in mpox cases, the Africa Centres for Disease Control has taken the unprecedented step of declaring the outbreak sweeping through African countries a continental public health emergency.

The World Health Organization (WHO) is also meeting to decide whether to trigger its highest global alert level over the epidemic.

These moves come after a virulent strain of the disease spread rapidly to 16 countries and six new countries were affected in 10 days.

Microsoft patches critical flaws in Azure Health Bot Service that could expose patient data. Researchers detail vulnerabilities and their potential im.

University of Missouri scientists are battling against an emerging enemy of human health: nanoplastics. Much smaller in size than the diameter of an average human hair, nanoplastics are invisible to the naked eye.

Columbia researchers discovered that bacteria can create free-floating, temporary genes outside their chromosomes, challenging the long-held belief that all genetic instructions are contained within the genome. This finding opens the possibility that similar genes could exist in humans, potentially revolutionizing our understanding of genetics and gene editing.

Since the genetic code was first deciphered in the 1960s, our genes have appeared like an open book. By interpreting our chromosomes as linear sequences of letters, akin to sentences in a novel, we can identify the genes within our genome and understand how changes in a gene’s code influence health.

This linear rule of life was thought to govern all forms of life—from humans down to bacteria.

In this interview, hosted by Nicolás Cherñavsky, Nir Barzilai and Brad Stanfield discuss metformin, whether or not to use it in non-diabetic patients to slow aging, and the TAME trial.

Nir Barzilai is president of the Academy of Health and Lifespan Research (https://www.ahlresearch.org/), and Brad Stanfield is a primary care physician in Auckland (New Zealand) and runs a YouTube channel (/ @drbradstanfield) with around 250,000 subscribers to explore the latest research and preventive care guidelines.

Continue reading “Metformin and the TAME trial: a conversation with Nir Barzilai and Brad Stanfield” »

In a new study, a molecule identified and synthesized by UCLA Health researchers was shown to restore cognitive functions in mice with symptoms of Alzheimer’s disease by effectively jumpstarting the brain’s memory circuitry.

If proven to have similar effects in humans, the candidate compound would be novel among Alzheimer’s disease treatments in its ability to revitalize memory and cognition, study authors said.

There is really nothing like this on the market or experimentally that has been shown to do this.

Fyodor Urnov explains how retuning genes can restore health harmony.

This new titanium heart has a mag lev inside to spin continuously and pump at the same rate as a normal heart.

Heart failure is a global epidemic affecting at least 26 million people worldwide, 6.2 million adults in the U.S., and is increasing in prevalence. Heart transplantations are reserved for those with severe heart failure and are limited to fewer than 6,000 procedures per year globally.

Consequently, the U.S. National Institutes of Health estimated that up to 100,000 patients could immediately benefit from mechanical circulatory support (MCS), and the European market is similarly sized. Without intervention, patients with severe HF have a bleak outlook. For these patients, drug therapy is a limited, relatively ineffective option. Although a heart transplant would meet their needs, only 6,000 donor hearts are available globally each year.

Continue reading “Replacing Hearts. Restoring Lives” »