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Legendary Doom developer John Carmack theorizes that the world’s tech could run on outdated hardware if it was properly optimized

Id Software co-founder and programmer John Carmack shared a theory that if „optimization was truly a priority… modern tech could run on outdated hardware.

Single enzyme streamlines production of all four RNA building blocks

A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been identified by researchers at the Institute of Science Tokyo. The study was published online in the journal Nature Communications.

By using polyphosphate as a phosphate donor, the enzyme efficiently converts inexpensive nucleotide precursors into the active forms required for RNA synthesis. Overall, the method dramatically simplifies the process of nucleotide production—offering a low-cost, efficient option for the in vitro synthesis of RNA.

Not just a pain in the bone

In a new Science study, researchers report an unexpected role for sensory nerves in bone healing, providing insights into communication between the nervous system and the cells responsible for bone repair.

Learn more in a new Science Perspective.


Growth factors secreted by sensory nerves promote fracture healing.

Vicki Rosen and Francesca Gori Authors Info & Affiliations

Science

Vol 391, Issue 6781

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