Gene hacking techniques that were recently used in human cells for the first time could someday let doctors shred up and destroy viruses like herpes or hepatitis B inside human cells, scientists say.
The new technique is called CRISPR-Cas3 — usually, when you hear about CRISPR tech, it’s the Cas9 variety — and Cornell researchers believe it could be used to cure viral diseases, according to a university-published press release.
“Julie has been associated with SENS since its earliest days: she participated in the first workshop that I organised to discuss it, in 2000, and she was a co-author on the first SENS paper in 2002. We’re delighted to be funding her laboratory at the Buck Institute to explore new ways of eliminating neurofibrillary tangles from neurons of Alzheimer’s sufferers, and at UA2019 we will hear about their initial progress.” says Aubrey de Grey.
https://www.undoing-aging.org/news/dr-julie-k-andersen-to-sp…Qq6fZbArkM #
Videos will be released step by step over the next few weeks as we receive clearance from the individual speakers.
This week we kick it off with Jerry Shay, who is the Vice Chairman of the Department of Cell Biology at The University of Texas Southwestern Medical Center in Dallas, presenting ‘Telomeres and Telomerase in Aging and Cancer‘.
undoing-aging.org/…/jerry-shay-presenting-at-undoing-aging-…
More info on Forever Healthy: forever-healthy.org
ETH researchers have integrated two CRISPR-Cas9-based core processors into human cells. This represents a huge step towards creating powerful biocomputers.
Controlling gene expression through gene switches based on a model borrowed from the digital world has long been one of the primary objectives of synthetic biology. The digital technique uses what are known as logic gates to process input signals, creating circuits where, for example, output signal C is produced only when input signals A and B are simultaneously present.
To date, biotechnologists had attempted to build such digital circuits with the help of protein gene switches in cells. However, these had some serious disadvantages: they were not very flexible, could accept only simple programming, and were capable of processing just one input at a time, such as a specific metabolic molecule. More complex computational processes in cells are thus possible only under certain conditions, are unreliable, and frequently fail.
There have been a number of efforts to increase genome diversity. In 2010, the US National Institutes of Health (NIH) and the Wellcome Trust in London launched the Human Heredity and Health in Africa (H3Africa) initiative, which supports Africa-led genome research. And last year, the NIH started enrolment for the All of Us research programme, which plans to collect DNA and health data from hundreds of thousands of people of varying ethnicities in the United States.
Researchers from under-represented groups are making genomics more inclusive by working with communities that have been overlooked or abused.
A physics-based, “atavistic” model posits that cancer is a “safe mode” for stressed cells and suggests that oxygen and immunotherapy are the best ways to beat the disease.
