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AI-designed drug to enter human clinical trial for first time

A drug molecule invented entirely by artificial intelligence is set to enter human clinical trials for the first time, marking a critical milestone for the role of machine learning in medicine.

The new compound, which has been designed to treat patients with obsessive-compulsive disorder, was developed by Oxford-based AI start-up Exscientia in collaboration with the Japanese pharmaceutical firm Sumitomo Dainippon Pharma.

In a sharp acceleration of the typical path to drug development, which can take about four and a half years, the AI-designed compound reached the point of entering clinical trials within just 12 months.

‘There’s no doubt’: Top US infectious disease doctor says Wuhan coronavirus can spread even when people have no symptoms

People without ANY symptoms can spread Wuhan Coronavirus.


The nation’s top infectious disease doctor says a new study published Thursday night shows people can spread the Wuhan coronavirus before symptoms set in.

German researchers found that the virus was transmitted by people without symptoms in five instances in one cluster of people: from a parent to a daughter; from that daughter to two colleagues; and from one of those colleagues to two other coworkers.

Preventing metastasis

Olivier Feron, a University of Louvain researcher, studies how cancer spreads through the body via metastasis. His major discovery was that cancer cells multiply by using lipids as food. His latest discovery, published in the scientific journal Nature Communications, is that lipid storage promotes cancer invasiveness. A new drug currently being tested to treat obesity may also help fight metastasis.

Rare clay used by B.C. aboriginals found to kill antibiotic-resistant bacteria

VANCOUVER — Researchers at the University of British Columbia have confirmed that a rare clay used as medicine by aboriginals in B.C. contains antibacterial properties that could be used to to treat antibiotic-resistant bacteria.

Some 400 kilometres north of Vancouver, on the Heiltsuk First Nation’s traditional territory, sits a 400-million kilogram deposit of glacial clay in Kisameet Bay that scientists believe was formed near the end of the last Ice Age, approximately 10,000 years ago.

The grey-green clay, known as Kisolite, has been used for centuries by the Heiltsuk First Nations to treat a range of ailments including ulcerative colitis, arthritis, neuritis, phlebitis, skin irritation, and burns. Locals also use the clay for eczema, acne and psoriasis.

Genomics and BioPharma Pioneer!! — Dr. William Haseltine — Biologist, entrepreneur and philanthropist, now focusing on the issues of healthcare costs, dementia care, and aging — ideaXme — Ira Pastor

From Blood to Bone (and Back)! — Dr. Rhonda Prisby — University of Texas, Arlington — Fascinating ossification research in the Bone Vascular and Micro-Circulation Laboratory — ideaXme — Ira Pastor

Dr Rhonda Prisby: From blood to bone and the connections between cardiovascular and skeletal systems

From Blood to Bone (and back)! — Dr. Rhonda Prisby, from University of Texas at Arlington, joins me on ideaXme (http://radioideaxme.com/) to discuss her fascinating research in the Bone Vascular and Micro-Circulation Laboratory, focusing on the unique interaction between vascular and skeletal systems, and novel disease states where vessels become bone-like “dead space”! — https://www.youtube.com/watch?v=PsK-pPjW020&t=1s #Ideaxme #Bone #Microcirculation #Vasculature #Ossification #Atherosclerosis #Parathyroid #Osteoblast #Osteoclast #Health #Wellness #Regeneration #Longevity #Aging #IraPastor #Bioquark #Regenerage


Ira Pastor, ideaXme exponential health ambassador, interviews Dr. Rhonda Prisby, Associate Professor in the Department of Kinesiology, at The University of Texas at Arlington.

Ira Pastor comments:

We have a fascinating show today focusing on the intersection of the cardiovascular system and the skeletal system.

We will be discussing interesting recent evidence that suggests a unique link between cardiovascular disease and osteoporosis, a disease in which both the density and quality of bone are reduced, where bones become more porous and fragile, and the risk of fracture is greatly increased.

Can Herbal Medicines Fight Wuhan Coronavirus?

Research over the past two decades shows that certain herbal medicines can fight the new Wuhan coronavirus contagion. Let’s review the evidence showing that certain plant medicines can fight similar viral infections such as SARS, MERS and Ebola, and why this can also apply to the Wuhan coronavirus

Let’s review some of the current science on this coronavirus infection. Then we can discuss what plant medicines can offer.

Latest on the Wuhan coronavirus.

Spinal injury researchers find a sweet spot for stem cell injections

As they do in many areas of medicine, stem cells hold great potential in treating injured spinal cords, but getting them where they need to go is a delicate undertaking. Scientists at the University of California San Diego (UCSD) are now reporting a breakthrough in this area, demonstrating a new injection technique in mice they say can deliver far larger doses of stem cells and avoid some of the dangers of current approaches.

The research focuses on the use of a type of stem cell known as a neural precursor cell, which can differentiate into different types of neural cells and hold great potential in repairing damaged spines. Currently, these are directly injected into the primary cord of nerve fibers called the spinal parenchyma.

“As such, there is an inherent risk of (further) spinal tissue injury or intraparechymal bleeding,” says Martin Marsala, professor in the Department of Anesthesiology at UCSD School of Medicine.

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