Lifeboat Foundation

Read the accompanying news item: https://www.humanbrainproject.eu/en/follow-hbp/news/ebrains-…disorders/

Using the EBRAINS research infrastructure, scientists of the Human Brain Project have developed multi-scale simulations of the human brain that mimic hallmarks of activity during wake and deep sleep states. Such simulations can lead to a better understanding of biological mechanisms that regulate human consciousness and its disorders, which span from single neurons to whole brain scales.

Ever hear of the Turk —the 19th-century mechanism topped by a turbaned head that played chess against all comers? In fact, hidden inside was a diminutive chessmaster, one you might imagine deadpanning, “Eh, It’s a living.”

Then there’s its namesake, the Mechanical Turk —a 21st-century service offered by Amazon to mark up images on the Web with the help of crowdsourced freelancers. They, too, might intone, glassy-eyed, “It’s a living.”

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HBP researchers have trained a large-scale model of the primary visual cortex of the mouse to solve visual tasks in a highly robust way. The model provides the basis for a new generation of neural network models. Due to their versatility and energy-efficient processing, these models can contribute to advances in neuromorphic computing.

Modeling the brain can have a massive impact on artificial intelligence (AI): since the brain processes images in a much more energy-efficient way than artificial networks, scientists take inspiration from neuroscience to create neural networks that function similarly to the biological ones to significantly save energy.

In that sense, brain-inspired neural networks are likely to have an impact on future technology, by serving as blueprints for visual processing in more energy-efficient neuromorphic hardware. Now, a study by Human Brain Project (HBP) researchers from the Graz University of Technology (Austria) showed how a large data-based model can reproduce a number of the brain’s visual processing capabilities in a versatile and accurate way. The results were published in the journal Science Advances.

More than a decade ago, scientists started finding peculiar droplets inside cells. Now researchers are trying to work out how these ubiquitous beads form and what they do.

Researchers from North Carolina State University have developed a new method for determining which genes are relevant to the aging process. The work was done in an animal species widely used as a model for genetic and biological research, but the finding has broader applications for research into the genetics of aging.

“There are a lot of genes out there that we still don’t know what they do, particularly in regard to aging,” says Adriana San Miguel, corresponding author of a paper on the work and an assistant professor of chemical and biomolecular engineering at NC State.

That’s because this field faces a very specific technical challenge: by the time you know whether an organism is going to live for a long time, it’s old and no longer able to reproduce. But the techniques we use to study genes require us to work with animals that are capable of reproducing, so we can study the role of specific genes in subsequent generations.

When we think about aging, one of the first thoughts that comes to mind is wrinkled and sagging skin as well as the greying and loss of hair – simply put, the physical changes to appearance that we associated with advancing age. These changes are the most striking reflection of the underlying molecular aging processes that are happening inside our bodies.

The current size of the cosmetic industry alone highlights that physical appearance is important to people. As we continue developing strategies to improve longevity allowing us to live longer and in far better health, people will inevitably want a “youthful appearance” to match their newfound “youthful state”. Furthermore, as this report explains in more detail, aesthetic aging plays a significant and grossly underappreciated role in influencing the rate of biological aging.

It is fair to say that the cosmetic industry alone might not be enough to address aesthetic aging from a longevity point of view, as cosmetic products work to conceal the signs of aging. We need tactics that can address the underlying causes of skin and hair aging to achieve long-term benefits and halt the fine interlink between aesthetic aging and biological aging. This is where advanced aesthetics comes in.

A group of scientists led by the U.S. Department of Energy’s National Renewable Energy Laboratory (NREL) in Golden and involving the University of Colorado Boulder has developed a new, eco-friendly method to produce ammonia, the main ingredient of fertilizer, using light.

The researchers discovered that light energy can be used to change dinitrogen (N2), a molecule made of two nitrogen atoms, to ammonia (NH3), a compound of nitrogen and hydrogen. The researchers hope the newly discovered, light-driven chemical process that creates ammonia can lead to future developments that will enhance global agricultural practices while decreasing the dependence of farmers on fossil fuels.

Traditionally there have been two main ways to transform nitrogen, the most common gas in Earth’s atmosphere, for use by living organisms. One is a biological process that occurs when atmospheric nitrogen is “fixed” by bacteria found in the roots of some plants like legumes and then converted to ammonia by an enzyme called nitrogenase.

Experiments have shown how the world’s hardiest microbe could endure freezing, dry and irradiated conditions on Mars.

Thanks to NASA, the world may soon have access to chargers that can top off an EV in as little as five minutes. One of the biggest obstacles to fast charging is dealing with temperature. According to NASA, for an EV to be charged in five minutes, the charger must deliver an electric current of 1,400 amperes. For reference, the fastest chargers currently available max out at around 520 amperes. More amperes equals more heat. A lot more heat. Companies and research organizations are pursuing solutions to the problem; Ford and Purdue University, for example, are exploring liquid-cooled charging cables.

A team sponsored by NASA’s Biological and Physical Sciences Division is working on technology that could provide another solution needed for ultra fast EV charging. The technology has been developed for use in space, in which massive temperature differentials require massive heat transfer capabilities. An experiment to prove the new tech, the Flow Boiling and Condensation Experiment (FBCE), was installed on the International Space Station and is providing data that NASA will use to determine if the system will provide the claimed orders-of-magnitude benefits in heat transfer efficiency.

We’re definitely not NASA-level engineers but we will try to explain the FBCE the best we can. The FBCE is made up of several modules; one of which is called a “Flow Boiling Module” (FBM). When cooling liquid inside the FBM begins to boil, the bubbles formed draw liquid from the inner part of the flow channel to its walls. The process “efficiently transfers heat by taking advantage of both the liquid’s lower temperature and the ensuing change of phase from liquid to vapor.” The technique has been dubbed “subcooled flow boiling.”