Lifeboat Foundation

A cloud-based repository that creates a digital fingerprint of engineered microorganisms has been successfully trialed.

An international team led by Newcastle University has launched CellRepo, a species and strain database that uses cell barcodes to monitor and track engineered organisms. Reported in a new study in the journal Nature Communications, the database keeps track and organizes the digital data produced during cell engineering. It also molecularly links that data to the associated living samples.

Available globally, this resource supports international collaboration and has significant safety advantages, such as limiting the impact of deliberately or accidentally released genetically modified microorganisms by enabling faster tracing of organisms lab of origin and design details.

Dr. Marvin Minsky — A.I. Pioneer & Mind Theorist. Professor of Media Arts and Sciences, MIT, Media Lab http://GF2045.com/speakers.

As soon as we understand how the human brain works, we should be able to make functional copies of our minds out of other materials. Given that everything is made of atoms, if you make a machine, in some sense it is made of the same kinds of materials as brains are made but organized either in very different ways or fundamentally the same ways.

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FeaturedRead our 3 books at https://spanish.lifeboat.com/ex/books.

The Lifeboat Foundation is a nonprofit nongovernmental organization dedicated to encouraging scientific advancements while helping humanity survive existential risks and possible misuse of increasingly powerful technologies, including genetic engineering, nanotechnology, and robotics/AI, as we move towards the Singularity.

Lifeboat Foundation is pursuing a variety of options, including helping to accelerate the development of technologies to defend humanity, such as new methods to combat viruses, effective nanotechnological defensive strategies, and even self-sustaining space colonies in case the other defensive strategies fail.

Continue reading “HumanityMars NEW YEAR 2030 PARTY IN MARS CITY!” »

“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” said Bennett.

The heart was provided by Revivicor, a company based in Virginia that has been engineering pig organs for roughly two decades. In several experiments for pig-to-baboon transplants, the organs survived up to nine months, until the animals passed away due to a lung infection unrelated to the transplant.

Overall, the heart had 10 hefty genetic edits. Three of them wiped out sugar molecules on the outside of cells that provoke an immune response. Six bolstered the chance of the human host accepting the heart—amping up an anti-inflammatory response, preventing blood vessel damage, and dampening any antibodies against the organ. Finally, the last edit limited the pig heart’s size. Although it generally matched the size of a human heart, the team wanted to prevent the pig organ from overgrowth inside Bennett’s chest once it was transplanted—something they previously noticed happened in baboons.

And it took less than a full workday. Stanford Medicine scientists and their collaborators have engineered a new genome sequencing technique that can diagnose rare genetic diseases in an average of eight hours. This is a record-breaking time frame that is leap and bounds ahead of other current advanced technologies.

Gene sequencing is crucial to advancing science! Check out why cutting time and cost is key.

Innovating Life-Saving Therapeutic Devices — Dr. Amy Throckmorton, PhD — BioCirc Research Laboratory, Drexel University School of Biomedical Engineering, Science and Health Systems.

Dr. Amy Throckmorton, Ph.D. (https://drexel.edu/biomed/faculty/core/ThrockmortonAmy/) is Associate Professor and Director of the BioCirc Research Laboratory, in the School of Biomedical Engineering, Science and Health Systems, at Drexel University.

Continue reading “Dr. Amy Throckmorton, PhD — BioCirc / Drexel University — Innovating Life-Saving Therapeutic Devices” »

I don’t know how about you… But I’m meeting cyborgs in the streets regularly. If you observe carefully you can find people with artificial legs and arms. So next time watch more carefully. Its most common seen artificial body part. On other hand there are other parts you can’t see, like artificial joints, dental implants, breast implants, pacemakers, insulin pumps and so on. We are unable to see them but they are very common. Millions people use them. Nowadays very common trend is biohacking where people implant magnets and chips to their bodies. We think our bodies are born complete but we are wrong. We can upgrade and modify them. What if we can use brain implants to be smarter, to think and focus sharper.

One critical difference? Unlike a Mars mission’s “seven minutes of terror,” during which the entry, descent, and landing occur too fast for human operators to interfere, gene therapy delivery is completely blind. Once inside the body, the entire flight sequence rests solely on the design of the carrier “spaceship.”

In other words, for gene therapy to work efficiently, smarter carriers are imperative.

This month, a team at Harvard led by Dr. David Liu launched a new generation of molecular carriers inspired by viruses. Dubbed engineered virus-like particles (eVLPs), these bubble-like carriers can deliver CRISPR and base editing components to a myriad of organs with minimal side effects.

Bronze Age bioengineers created the earliest hybrid animal — a majestic horselike creature known as a kunga that had a donkey mom, a Syrian wild ass for a father and lived 4,500 years ago, according to new research based on the sequencing of DNA from the animal’s skeleton.

Descriptions and imagery in Mesopotamian art and texts portray a powerful animal that pulled war wagons into battle and royal vehicles in parades. Its true identity, however, had long puzzled and divided archaeologists. Domesticated horses didn’t arrive in the region, sometimes referred to as the Fertile Crescent, until 4,000 years ago.