Lifeboat Foundation

Excellent read and a true point about the need for some additional data laws with our ever exploding information overload world.

Laws for Mobility, IoT, Artificial Intelligence and Intelligent Process Automation

If you are the VP of Sales, it is quite likely you want and need to know up to date sales numbers, pipeline status and forecasts. If you are meeting with a prospect to close a deal, it is quite likely that having up to date business intelligence and CRM information would be useful. Likewise traveling to a remote job site to check on the progress of an engineering project is also an obvious trigger that you will need the latest project information. Developing solutions integrated with mobile applications that can anticipate your needs based upon your Code Halo data, the information that surrounds people, organizations, projects, activities and devices, and acting upon it automatically is where a large amount of productivity gains will be found in the future.

Continue reading “Laws for Mobility, IoT, Artificial Intelligence” »

Scientists are now one step closer to neutralizing HIV.

In a study conducted at Vanderbilt University and published in Proceedings of the National Academy of Sciences, researchers isolated antibodies with a loop-like structure that binds tightly to HIV and disables it. Unlike traditional vaccines, which jump-start an immune response by exposing the patient to a pathogen, this newly discovered method could work even in people who have not previously been exposed to by the virus.

Using computer modeling, the researchers identified the amino acid sequences that bound most tightly to HIV and re-engineered them in an optimal sequence that simulated vaccination.

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New research by UCSF scientists could accelerate – by 10 to 100-fold – the pace of many efforts to profile gene activity, ranging from basic research into how to build new tissues from stem cells to clinical efforts to detect cancer or auto-immune diseases by profiling single cells in a tiny drop of blood.

The study, published online April 27, 2016, in the journal Cell Systems, rigorously demonstrates how to extract high-quality information about the patterns of gene expression in individual cells without using expensive and time-consuming deep-sequencing technology. The paper’s senior authors are Hana El-Samad, PhD, an associate professor of biochemistry and biophysics at UCSF, and Matt Thomson, PhD, a faculty fellow in UCSF’s Center for Systems and Synthetic Biology.

“We believe the implications are huge because of the fundamental tradeoff between depth of sequencing and throughput, or cost,” said El-Samad. “For example, suddenly, one can think of profiling a whole tumor at the single cell level.”

In a new study, researchers detail the culturing and transfecting of cells with genetic material on an array of carbon nanotubes, which appears to overcome the limitations of other gene editing technologies.

Gene editing techniques hold great promise. They allow targeted and specific edits of genes, and have nearly limitless possibilities in the field of medicine.

Which is not to say that they are perfect. These techniques still have a range of limitations, from precision to toxicity. But a new study shows that can be changed.

Continue reading “Gene Editing Made Easier, Thanks to Carbon Nanotubes” »

Bioquark, Inc., (http://www.bioquark.com) a company focused on the development of novel biologics for complex regeneration and disease reversion, and Revita Life Sciences, (http://revitalife.co.in) a biotechnology company focused on translational therapeutic applications of autologous stem cells, have announced that they have received IRB approval for a study focusing on a novel combinatorial approach to clinical intervention in the state of brain death in humans.

This first trial, within the portfolio of Bioquark’s Reanima Project (http://www.reanima.tech) is entitled “Non-randomized, Open-labeled, Interventional, Single Group, Proof of Concept Study With Multi-modality Approach in Cases of Brain Death Due to Traumatic Brain Injury Having Diffuse Axonal Injury” (https://clinicaltrials.gov/ct2/show/NCT02742857?term=bioquark&rank=1), will enroll an initial 20 subjects, and be conducted at Anupam Hospital in Rudrapur, Uttarakhand India.

Continue reading “Bioquark Inc. and Revita Life Sciences Receive IRB Approval for First-In-Human Brain Death Study” »

CRISPR to improve shelf life of vegetables and fruits. I magine what this would mean for populations in remote locations with horrible climates or in disaster zones that need fresh foods.

Yinong Yang, a Penn State University researcher, has used a famous gene editing tool known as CRISPR/Cas9 for cutting out a small piece of DNA from one specific gene in a white button mushroom. With this, Yang was able to stop the gene, which in turn cuts the production of an enzyme known as polyphenol oxidase in mushroom. With this gene editing of white mushrooms, the mushroom doesn’t get spoiled as natural mushrooms.

You might have heard something like this earlier as scientists have also developed non-browning versions of apples and potatoes. However, those crops were called GMOs as scientists had put in new, slightly altered genes within those plants to ‘silence’ the natural gene.

Continue reading “Penn Researcher uses CRISPR/Cas9 to snip out tiny piece of DNA from gene in white button mushroom” »

Another gene editing triumph.

Genetic engineering may emerge as an important tool to avert extinctions. But ecosystems are complex, and this tinkering might not unfold as planned.

I was asked recently if I had money given to me to invest in anything that would result in the betterment of people what would that be. I quickly shared “Gene Editing” such as CRISPR and Quantum. These 2 areas is changing our lives over the next 7 to 10 years in ways that we have only dreamed about. I love this article.

TENS of thousands of blind people could have their sight restored after scientists discovered how to manipulate genes at the back of the eyes.

(Phys.org)—A new study shows that a swarm of hundreds of thousands of tiny microbots, each smaller than the width of a human hair, can be deployed into industrial wastewater to absorb and remove toxic heavy metals. The researchers found that the microbots can remove 95% of the lead in polluted water in one hour, and can be reused multiple times, potentially offering a more effective and economical way to remove heavy metals than previous methods.

The researchers, Diana Vilela, et al., have published a paper on the lead-adsorbing microbots in a recent issue of Nano Letters.

“This work is a step toward the development of smart remediation system where we can target and remove traces of pollutant without producing an additional contamination,” coauthor Samuel Sánchez, at the Max-Planck Institute for Intelligent Systems in Stuttgart, Germany; the Institute for Bioengineering of Catalonia in Barcelona; and the Catalan Institution for Research and Advanced Studies in Barcelona, told Phys.org.