Dec 15, 2023

Interpretable neural architecture search and transfer learning for understanding CRISPR–Cas9 off-target enzymatic reactions

Posted by in categories: biotech/medical, neuroscience

Developing predictive mechanistic models in biology is challenging. Elektrum uses neural architecture search, kinetic models and transfer learning to discover CRISPR–Cas9 cleavage kinetics, achieving high performance and biophysical interpretability.

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