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Sep 19, 2023

Drug delivery systems for CRISPR-based genome editors

Posted by in categories: biotech/medical, genetics, nanotechnology

CRISPR-based genome editing has the potential to treat many human genetic diseases, but achieving stable, efficient and safe in vivo delivery remains a challenge. This Review assesses current delivery systems for genome editors—focusing on adeno-associated viruses and lipid nanoparticles—and highlights data from recent clinical trials. Emerging delivery systems and ongoing challenges in the field are discussed.

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