Jan 18, 2023

Simulating Cellular Evolution: The Path To Multicellularity

Posted by in categories: biotech/medical, evolution, genetics

In this video I showcase a program that I have been working on for simulating evolution by natural selection. I dive into various mechanisms of the simulation and go over some interesting real-life biology in the process. The key aim of this project is to evolve multicellular organisms, starting from single-celled protozoa-like creatures that must collect mass and energy from their surroundings in order to survive, grow and reproduce.

00:00 — Introduction.
00:56 — Life of a protozoan.
02:46 — The start of the simulation.
05:57 — How the cells work.
06:53 — Introducing multicellular colonies.
08:33 — Understanding evolution.
11:38 — Looking at data from the simulation.
13:27 — Evolving epigenetics introduction.
14:14 — Waddington’s Landscape and cell specialisation.
15:22 — The Central Dogma of Molecular Biology.
16:05 — Gene Regulatory Networks.
16:54 — Outro.
17:30 — Watching the simulation.

Find the project on GitHub:


Tectonic plates animation: Scotese, C.R., 2016. Plate Tectonics, Paleogeography, and Ice Ages, (Modern World — 540Ma)

Gene expression and cell specialisation diagram: Prof. Dave Explains, 2017. The origin of multicellular life.

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