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Jan 14, 2023

Loss of epigenetic information as a cause of mammalian aging

Posted by in categories: biotech/medical, genetics, life extension

Aging is characterized by changes in cellular identity and function over time. This process is driven by changes in chromatin factor localization during DNA break repair, which alters the epigenome and advances the epigenetic clock. Expression of a subset of Yamanka factors, OSK, can reverse these changes and modulate aging.

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