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Nov 29, 2022

Scientists have solved the mystery of male rats without Y chromosomes

Posted by in category: futurism

The Y chromosome carries a gene called SRY, which turns on male genes on other chromosomes.

The Amami spiny rat, one of the species that lack a Y chromosome and the Sry.

As per the press release, under normal conditions, the Sry gene on the Y chromosome triggers the formation of the testes. However, the Sry gene, along with the Y chromosome, has vanished in a small number of rodent species.


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By upregulating Sox9 in the absence of Sry, the researchers found that the sequence duplication in Amami spiny rats was a novel regulatory factor.

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