Professor Emanuele Montomoli
The Reuters article Monkey cells used for bird flu vaccine said
A bird flu vaccine made from monkey cells instead of chicken eggs has been reported effective by corporate researchers.
The researchers, from drug company Baxter International, documented the use of monkey cells as a safe alternative for influenza vaccinations.
“Cell culture technology could represent the future of influenza vaccine production,” said virologist John Oxford of The Queen Mary School of Medicine in London.
Scientists had previously been using chicken eggs but they found it difficult to obtain the right type and observed that the virus, H5N1, kills chickens rapidly.
Emanuele Montomoli, Ph.D. was one of these researchers and is
Professor, Public Health, Lab Molecular Epidemiology, University of
Siena, Italy.
Emanuele has extensive experience in respiratory viruses,
particularly influenza. Since 1994 he has been carrying out
seroepidemiological research for evaluating the immune status of the
population toward influenza viruses. Since 1995 he has mostly overseen
clinical trials of vaccines, evaluating their immunogenicity and
reactogenicity.
His recent research is focused on the
molecular
epidemiology of respiratory viruses, particularly the influenza and
avian influenza strains. Currently, his research interests are focused
on the standardization of serological assays for vaccine immune response
evaluation. He is the author of approximately thirty articles, as well
as numerous abstracts and letters, published in Italian and
international scientific journals.
He coauthored
A Clinical Trial of a Whole-Virus H5N1 Vaccine Derived from Cell
Culture,
Prevalence of antibodies to Vaccinia virus after smallpox vaccination
in
Italy,
Influenza-related mortality in the Italian elderly: No decline
associated with increasing vaccination coverage,
Impact of routine infant and adolescent hepatitis B vaccination in
Tuscany, Central Italy,
Combination adjuvants for the induction of potent, long-lasting
antibody
and T-cell responses to influenza vaccine in mice,
Pre-emptive vaccination against pandemic influenza virus,
Cross-protection by MF59&tm;adjuvanted influenza vaccine:
Neutralizing
and
haemagglutination-inhibiting antibody activity against A(H3N2) drifted
influenza viruses, and
Susceptibility to varicella in childbearing age women, Central Italy:
Is
there a need for vaccinating this population group?
Read the
full list of his publications!
Emanuele graduated in 1988 from the Technical School in Siena as an expert
industrial chemist.
In 1997 he earned a MSc. in Biology
at the Physical Mathematical and
Natural Science Faculty of the University of Siena with the thesis
“Optimization of the
use of MDCK cell cultures (Madin Darby canine kidney) for the
epidemiological control of influenza”.
In 2002 he earned a Ph.D. in Biochemistry and Enzymology at the
School of Siena University with the thesis
“Purification of
hemoagglutinin of the type B influenza virus through isoelectric
focalization”.