Bill Faloon discusses advancements in age reversal therapies and their transition from research to clinical application, emphasizing the potential for delaying and reversing biological aging. He highlights advancements in age reversal, discussing therapies like young plasma, gene editing, yamanaka factors and exosome treatments, emphasizing their potential to reverse aging, improve health, and extend lifespan.
Credits to : Age Reversal Network https://age-reversal.net/
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]]>Unlock the Secret to a Longer, Healthier Life: The Power of Inhibiting IL-11
Discover the groundbreaking science behind aging in this video, Mr. Bill Faloon presents:
• The Role of IL-11 in Aging: Learn how this inflammatory cytokine accelerates aging and contributes to age-related diseases.
• The Benefits of Inhibiting IL-11: Discover how reducing IL-11 levels can lead to increased lifespan, improved health, and a more youthful appearance.
• Natural Ways to Inhibit IL-11: Learn about dietary supplements and lifestyle habits that can help you lower IL-11 levels.
• The Future of Anti-Aging Medicine: Explore the latest research on drugs and therapies targeting IL-11 and how they may revolutionize the way we approach aging.
https://www.nature.com/articles/s41586-024-07701-9
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9386112/
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10754292/
Understanding interleukin 11 as a disease gene and therapeutic target.
https://neurosciencenews.com/inflammation-il11-longevity-26458/
Blocking Inflammation Protein Extends Lifespan.
https://www.telegraph.co.uk/news/2024/07/17/scientists-find-…op-cancer/
]]>This has to do with E5, but last I checked they were only doing skin rejuvenation treatments in people.
In Aging Cell, researchers have published their findings that exosomes, which we have previously reported to extend the lives of mice, also extend the lives of rats.
Known to be effective
Exosomes, a subset of extracellular vesicles (EVs), can be visualized as messages and packages that cells send to one another. Along with lifespan studies, EVs have been investigated for their ability to treat liver fibrosis, and they have been identified as potential biomarkers of disease [1].
]]>https://www.youtube.com/watch?v=AnlS1ATi5qU
Haven’t heard from Bill Andrews in awhile.
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Here we talk with Dr Bill Andrews all about telomeres, why they are on the critical path of aging and finding a way to lengthen them is required in an complete longevity solution.
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Chapters.
00:00 Why telomeres.
07:10 Telomeres and aging.
14:36 Telomerase in stem cells.
20:15 BiOptimizers.
21:44 Telomere shortening.
23:25 Measuring telomere length.
25:30 Biological age.
30:30 Slowing telomere shortening.
39:30 Supplements to help.
41:30 Sierra Science Chemicals \& Gene therapy.
49:30 How is telomerase repressed.
56:10 Liz Parrish \& Gene therapy.
1:01:40 Gene therapy delivery.
1:09:20 Telomerase \& cancer.
1:17:00 Why aging.
1:20:30 Telomeres \& senescence.
1:24:30 More information.
Links in this video.
Sierra Science home page https://sierrasci.com/
Dr Kaufmann’s books on Amazon.
The Kaufmann Protocol : https://amzn.to/3YqpbPB
The Kaufmann Protocol: Aging Solutions : https://amzn.to/3NJ2Oje.
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Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. Please consult with your doctor first. Products or services mentioned in this video are not a recommendation.
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#telomeres #telomerase #genetherapy
This is about life expectancy, not radical life extension.
A new study has suggested that radical life extension is all but impossible in this century [1], and it has made waves among people interested in living longer.
A paper titled “Implausibility of radical life extension in humans in the twenty-first century” was destined to ignite controversy in the longevity community. Published in Nature Aging, it lists Jay Olshansky as its corresponding author, a renowned researcher who has been studying the populational dynamics of life expectancy for decades. We delved deeper into this study and reached several prominent community members for comments.
]]>She’s been doing stem cell therapy for 8 years. She is 53.
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
]]>Next trial will be 10 dogs. And human trials for osteo-arthritis in late 2025.
SARASOTA, Fla. (WWSB) — We’ve all heard the phrase 50 is the new 40″ but what if 90 became the new 40? It may sound like science fiction but authors of a new age reversal study on dogs say it could be closer than you think.
One Suncoast rescue organization was granted permission to use the age reversal pill on two of it’s senior dogs struggling with health issues.
Less than six months ago, 12-year-old German Shepard Zeus was near death. His caretaker, Marsha Panuce at Donte’s Den in Myakka City, says she woke up one morning in March to find the dog clinging to life.
]]>Join Jeff Bezos for a tour inside Blue Origin’s New Glenn Production Facility at Cape Canaveral, Florida. This video was shot on May 30th, 2024.
00:00 — Intro.
00:40 — Interview Starts [Lobby]
05:20 — Recovering Saturn V Engines.
08:35 — Tank Production.
16:40 — Second Stage.
23:50 — Aft Section.
33:15 — Forward Section.
42:08 — Machine Shop.
51:35 — Payload Adapter and Fairings.
1:00:00 — Engines.
1:11:20 — Outro.
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https://everydayastronaut.com/shop/
All music is original! Check out my album \.
]]>Not in leading research but interesting.
According to a new study, a polyphenol-rich natural extract positively impacts lifespan, healthspan, and cellular senescence. These results were observed in both cell culture and a mouse model [1].
Traditional and folk medicines offer many botanical extracts that can be tested by modern science for their medicinal properties and influences on aging. One such plant is the Bolivian prawn sage (Salvia haenkei).
]]>There’s only one alliterative phrase i like more than ‘the sheekey science show’, and that’s ‘anti-aging antibodies’. now, as it happens, one thing i spent a lot of time working on this year is antibodies. Antibody, make me feel this way. now while i cannot tell you yet what i was/am doing, i can tell you about two recent science stories that exploit antibodies to extend mouse lifespan. Firstly, i will bring your attention to this paper — immunotherapy targeting isoDGR-protein damage extends lifespan and then we’ll look at this paper that came out last month — Inhibition of IL-11 signalling extends mammalian healthspan.
Find me on Twitter — / eleanorsheekey.
Support the channel.
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through Patreon — / thesheekeyscienceshow.
TIMESTAMPS:
Intro — 00:00
Antibodies — 00:45
Inhibiting protein damage — 02:15
Inhibiting IL-11 — 05:20
REFERENCES
Immunotherapy targeting isoDGR‐protein damage extends lifespan in a mouse model of protein deamidation — https://doi.org/10.15252/emmm.202318526
Widjaja, A.A., Lim, WW., Viswanathan, S. et al. Inhibition of IL-11 signalling extends mammalian healthspan and lifespan. Nature 632157–165 (2024). https://doi.org/10.1038/s41586-024-07…
Please note that The Sheekey Science Show is distinct from Eleanor Sheekey’s teaching and research roles. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Sheekey Science Show and guests assume no liability for the application of the information discussed.
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